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. 2022 Mar 31;13:677202. doi: 10.3389/fendo.2022.677202

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Copyright © 2022 Zhang, Hu, An, Wang, Liu and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Chord diagrams of significant (P<0.05) pairwise correlations between lipids for the control group (A), T2DM patients before exenatide treatment (B), and T2DM patients after exenatide treatment (C) respectively. The colored arcs outside of the circle represent 6 lipid classes. Significant correlations between every pair of lipid species are depicted by sectors, with red representing positive correlation and green representing negative correlation. Bandwidth corresponds to the number of correlated pairs. LPC, lysophosphatidylcholine; PE, phosphatidylethanolamine; LPE, lysophosphatidylethanolamine; PC, phosphatidylcholine; SM, sphingomyelin; Cer, ceramide.