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RBD interfacial residues primarily participate in interaction with ACE2. Superimposed images of WT with (a) Alpha, (b) Beta (c) Gamma, and (d) Delta. Color scheme: WT (cyan), Alpha (green), Beta (blue) Gamma (red), and Delta (magenta). Negative displacement was prominently seen in Gamma while Beta and Delta moved towards the ACE2 receptor. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)
