Table 3b.

Residue-wise interaction energies of the interfacial residues of ACE2 in RBD/ACE2 complex for the systems under study.

Residue	WT	Alpha	Beta	Gamma	Delta
Glu22	−19.83	−20.93	−37.96	−42.19	−57.74
Glu23	−20.82	−29.77	−53.33	−76.61	−84.16
Glu24	−15.59	−14.19	−16.17	−15.88	−15.73
Thr27	−13.36	−12.33	−13.08	−12.29	−15.02
Asp30	−51.24	−55.64	−12.26	−64.51	−97.39
Lys31	−31.88	−30.84	−87.24	54.25	27.88
His34	−32.51	−32.69	−12.26	−15.59	−18.84
Glu35	−16.66	−22.56	−87.24	−94.12	−78.44
Glu37	−12.06	−79.44	−92.53	−70.72	−98.38
Asp38	−12.16	−50.41	−96.32	−86.23	−115.92
Tyr41	−12.06	−12.83	−12.65	−7.63	−10.51
Gln42	−12.16	−4.78	−7.16	−2.77	−8.45
Glu56	−24.91	−17.40	−37.09	−33.98	−40.61
Glu57	−35.16	−24.04	−48.73	−45.94	−54.36
Asp67	−21.14	−16.88	−53.30	−47.74	−48.85
Glu75	−6.01	−8.051	−104.24	−74.85	−49.54
Tyr83	−17.99	−12.30	−13.36	−12.49	−13.81