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. Author manuscript; available in PMC: 2022 Apr 14.
Published in final edited form as: Biomater Sci. 2021 Feb 23;9(8):2768–2803. doi: 10.1039/d0bm01972k

Fig. 18.

Fig. 18

Carbon dot-passivated black phosphorus nanosheet hybrids for synergistic cancer therapy in the NIR-II window. (a) NIR-II-CD-loaded BP nanosheet preparation and morphology. TEM images of (b) pristine BP nanosheets and (c) NIR-II-CD/BP hybrids. (d) Schematic illustration of the NIR-IICD/BP hybrid energy position. (e) NIR-II-CDs, BP, and NIR-II-CD/BP temperature elevation upon 1064 nm laser irradiation at the same concentration. (f) In vitro deep-tissue PTT schematic illustration. (g) The temperature change of NIR-II-CD/BP solution irradiated by a 1064 nm laser. (h) Exponential decay of fitted temperature change of NIR-II-CD/BP hybrids upon 808 and 1064 nm laser irradiation. (i) Confocal pictures of HeLa cells cultured with NIR-II-CD/DOX/BP at pH 5.0 and 7.4. (j) NIR-II-CD/DOX/BP fluorescence image formation in vivo. (k) The PCT impact of NIR-II-CD/DOX/BP at 1064 nm. (l) Photographs of mice after receiving PCT treatment. Reproduced with permission.145 Copyright 2019, American Chemical Society.