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. 2022 Apr 14;2022(4):CD013696. doi: 10.1002/14651858.CD013696.pub2

Bricker 2014a.

Study characteristics
Methods Study design: RCT
Location: USA
Setting: community
Recruitment: uninsured callers to the South Carolina State Quitline
Study dates: 2012‐13
Participants N = 121
Specialist population?: uninsured
Definition of smoker used: ≥ 10 cpd for at least the past 12 months
Participant characteristics: 69% female; average age: 39 years; 73% white; 55% high school education or less; nicotine dependence: 71% HSI score ≥ 4; 39% positive depression screen
Interventions Comparator: standard CBT‐based counselling intervention offered through the South Carolina State Quitline
Mode of delivery: telephone
Intensity: 5 calls (1 x 30 min, 4 x 15 min)
Pharmacotherapy: 2 weeks of nicotine patch or gum (participant’s choice)
Type of therapist/provider: bachelor's‐ or master's‐level providers with ≥ 3 years of general counselling experience and > 100 h of training
BCTs: 1.2 Problem solving, 1.4 Action planning, 3.1 Social support (unspecified), 11.1: Pharmacological support, 12.4 Distraction
Intervention: ACT programme
  • The acceptance components taught skills in

    • increasing willingness to experience urges that cue smoking

    • changing the function of smoking urges

    • responding differently to smoking urges (e.g. noticing and not acting on urges).

  • The commitment components focused on helping individuals articulate the values guiding quitting and taking actions to quit guided by those values


Mode of delivery: telephone
Intensity: 5 calls (1 x 30 min, 4 x 15 min)
Pharmacotherapy: 2 weeks of nicotine patch or gum (participant’s choice)
Type of therapist/provider: bachelor's‐ or master's‐level providers with ≥ 3 years of general counselling experience and > 100 h of training
BCTs: 1.4 Action planning, 3.1 Social support (unspecified), 11.1: Pharmacological support
Outcomes Definition of abstinence: 30‐day point prevalence
Longest follow‐up: 6 months
Biochemical verification: none
Other relevant outcomes reported: none
Notes Relevant comparisons: ACT (telephone) + NRT vs CBT (quitline) + NRT
Funding source: National Institute on Drug Abuse (R21DA030646)
Author conflicts of interest: “In 2011 Dr. Heffner served as a consultant for Pfizer.”
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Randomised by automated algorithm
Allocation concealment (selection bias) Low risk Quote: “Randomized study arm assignments were computer generated and concealed from participants after eligibility was determined and consent for participation was obtained. Neither research staff nor participants had access to upcoming randomized study arm assignments”
Blinding of outcome assessment (detection bias)
All outcomes Low risk Abstinence self‐reported but no face‐to‐face contact so no difference in intensity; differential report unlikely
Incomplete outcome data (attrition bias)
All outcomes Low risk At 6‐month follow‐up 27.1% (16/59) were lost to follow‐up in the intervention group and 38.7% (24/62) in the control group
Selective reporting (reporting bias) Low risk Prespecified outcomes reported