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. 2021 Aug 13;163(5):861–877. doi: 10.1097/j.pain.0000000000002438

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Copyright © 2021 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the International Association for the Study of Pain.

This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

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Figure 4. — Histological evaluation of colon damage after the antibiotic regimen and the FMT. Macroscopic damage score (left panel) and representative microphotograph of haematoxylin or eosin-stained colon slices. Each value represents the mean ± SEM of 6 (A - day 7 and B - day 32) or 4 (C - day 46) animals per group. Statistical analysis was one-way analysis of variance followed by Bonferroni post hoc comparison. **P < 0.01 vs vehicle-treated animals. abx, antibiotics; CTR, control animals; DNBS, dinitrobenzenesulfonic acid; FMT, faecal microbiota transplantation.