Table 1.
Demographics.
| Normal Aging Cohort | Normal Aging Cohort (Age>60) | Preclinical AD Cohort | |
|---|---|---|---|
| n | 383 | 192 | 115 |
| n by Data Source | |||
| DIAN | 134 | 0 | 0 |
| OASIS | 249 | 192 | 115 |
| Age (median) | 18-88 (60) | 60-88 (70) | 61-89 (74) |
| Gender (% M) | 35.8 | 33.9 | 47.8 |
| MMSE (median) | 24-30 (30)a | 26-30 (30) | 23-30 (29) |
| APOE4 (% with an e4 allele) | 24.8 | 22.4 | 55.6 |
| Race (% Caucasian) | 89.8a | 89.1 | 90.4 |
| Education (years) (median) | 9-22 (16) | 10-20 (16) | 8-20 (16) |
| Amyloid Mean Cortical SUVR rsf – Centiloid (median) | −9.34-19.0 (−0.880)a | −9.34-19.0 (−0.453) | 16.4-141 (63.4) |
a
indicates missing data: 2 MMSEs, 6 Races, and 124 Amyloid (all from those under age 45) from the Normal Aging Cohort