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. 2022 Apr 14;25(2):370–372. doi: 10.1038/s41391-022-00542-5

Table 1.

Differences in prostate inflammation and prostate cancer according to COVID-19 infections after prostate biopsy.

Overall No COVID COVID+ p value
Results after prostate biopsy
 Age (Years) 69 (62–73) 69 (63–72) 68 (60–73) 1
 PSA at biopsy (ng/ml) 6.1 (4.5–9.1) 6.1 (4.4–7.7) 7 (4.6–10.4) 0.5
 Prostate volume (ml) 50 (19–163) 50 (19–163) 46 (23–116) 0.3
PSA density (ng/ml/cc) 0.09 (0.05–0.36) 0.10 (0.06–0.18) 0.09 (0.05–0.36) 0.7
Irani score (G) n (%) 0 2 (10) 1 (10) 1 (10) 0.1
1 8 (40) 6 (60) 2 (20)
2 10 (50) 3 (30) 7 (70)
Irani score (A) n (%) 0 7 (35) 4 (40) 3 (30) 0.3
1 10 (50) 4 (40) 6 (60)
2 2 (10) 2 (20) 0 (0)
3 1 (5) 0 (0) 1 (10)
Irani score (G + A) n (%) 0 2 (10) 1 (10) 1 (10) 0.5
1 2 (10) 1 (10) 1 (10)
2 7 (35) 5 (50) 2 (20)
3 8 (40) 3 (30) 5 (50)
4 0 (0) 0 (0) 0 (0)
5 1 (5) 0 (0) 1 (10)
Inflammatory cell infiltration n (%) Lympho mononuclear infiltration 20 (100) 10 (100) 10 (100)
Results after prostatectomy
Post-operative PSA (ng/ml) 0.02 (0.01–0.02) 0.02 (0.01–0.02) 0.02 (0.01–0.02) 0.1
Gleason Score at Radical Prostatectomy (n, %) 3 + 3 6 (30%) 3 (30%) 3 (30%) 1
3 + 4 14 (70%) 7 (70%) 7 (70%)
Inflammatory cell infiltration n (%) Lympho mononuclear infiltration 18 (90) 9 (90) 9 (90) 0.4
Granulomatous inflammation 1 (5) 1 (10) 0 (0)
Lympho mononuclear infiltration and granulomatous inflammation 1 (5) 0 (0) 1 (10)
Irani score prostate (G) n (%) 0 2 (10) 1 (10) 1 (10) 0.2
1 8 (40) 6 (60) 2 (20)
2 10 (50) 3 (30) 7 (70)
Irani score prostate (A) n (%) 0 7 (35) 4 (40) 3 (30) 0.3
1 10 (50) 4 (40) 6 (60)
2 2 (10) 2 (20) 0 (0)
3 1 (5) 0 (0) 1 (10)
Irani score prostate (G + A) n (%) 0 0 (0) 0 (0) 0 (0) 0.5
1 0 (0) 0 (0) 0 (0)
2 1 (5) 1 (10) 0 (0)
3 4 (20) 2 (20) 2 (20)
4 10 (50) 4 (40) 6 (60)
5 4 (20) 3 (30) 1 (10)
6 1 (5) 0 (0) 1 (10)
Delta IRANI score [(IRANI Prostatectomy – IRANI Biopsy)/IRANI Prostatectomy] 45% (25–50%) 50% (40–50%) 32.5 (25–50%) 0.7