Table 1.
Differences in prostate inflammation and prostate cancer according to COVID-19 infections after prostate biopsy.
Overall | No COVID | COVID+ | p value | ||
---|---|---|---|---|---|
Results after prostate biopsy | |||||
Age (Years) | 69 (62–73) | 69 (63–72) | 68 (60–73) | 1 | |
PSA at biopsy (ng/ml) | 6.1 (4.5–9.1) | 6.1 (4.4–7.7) | 7 (4.6–10.4) | 0.5 | |
Prostate volume (ml) | 50 (19–163) | 50 (19–163) | 46 (23–116) | 0.3 | |
PSA density (ng/ml/cc) | 0.09 (0.05–0.36) | 0.10 (0.06–0.18) | 0.09 (0.05–0.36) | 0.7 | |
Irani score (G) n (%) | 0 | 2 (10) | 1 (10) | 1 (10) | 0.1 |
1 | 8 (40) | 6 (60) | 2 (20) | ||
2 | 10 (50) | 3 (30) | 7 (70) | ||
Irani score (A) n (%) | 0 | 7 (35) | 4 (40) | 3 (30) | 0.3 |
1 | 10 (50) | 4 (40) | 6 (60) | ||
2 | 2 (10) | 2 (20) | 0 (0) | ||
3 | 1 (5) | 0 (0) | 1 (10) | ||
Irani score (G + A) n (%) | 0 | 2 (10) | 1 (10) | 1 (10) | 0.5 |
1 | 2 (10) | 1 (10) | 1 (10) | ||
2 | 7 (35) | 5 (50) | 2 (20) | ||
3 | 8 (40) | 3 (30) | 5 (50) | ||
4 | 0 (0) | 0 (0) | 0 (0) | ||
5 | 1 (5) | 0 (0) | 1 (10) | ||
Inflammatory cell infiltration n (%) | Lympho mononuclear infiltration | 20 (100) | 10 (100) | 10 (100) | |
Results after prostatectomy | |||||
Post-operative PSA (ng/ml) | 0.02 (0.01–0.02) | 0.02 (0.01–0.02) | 0.02 (0.01–0.02) | 0.1 | |
Gleason Score at Radical Prostatectomy (n, %) | 3 + 3 | 6 (30%) | 3 (30%) | 3 (30%) | 1 |
3 + 4 | 14 (70%) | 7 (70%) | 7 (70%) | ||
Inflammatory cell infiltration n (%) | Lympho mononuclear infiltration | 18 (90) | 9 (90) | 9 (90) | 0.4 |
Granulomatous inflammation | 1 (5) | 1 (10) | 0 (0) | ||
Lympho mononuclear infiltration and granulomatous inflammation | 1 (5) | 0 (0) | 1 (10) | ||
Irani score prostate (G) n (%) | 0 | 2 (10) | 1 (10) | 1 (10) | 0.2 |
1 | 8 (40) | 6 (60) | 2 (20) | ||
2 | 10 (50) | 3 (30) | 7 (70) | ||
Irani score prostate (A) n (%) | 0 | 7 (35) | 4 (40) | 3 (30) | 0.3 |
1 | 10 (50) | 4 (40) | 6 (60) | ||
2 | 2 (10) | 2 (20) | 0 (0) | ||
3 | 1 (5) | 0 (0) | 1 (10) | ||
Irani score prostate (G + A) n (%) | 0 | 0 (0) | 0 (0) | 0 (0) | 0.5 |
1 | 0 (0) | 0 (0) | 0 (0) | ||
2 | 1 (5) | 1 (10) | 0 (0) | ||
3 | 4 (20) | 2 (20) | 2 (20) | ||
4 | 10 (50) | 4 (40) | 6 (60) | ||
5 | 4 (20) | 3 (30) | 1 (10) | ||
6 | 1 (5) | 0 (0) | 1 (10) | ||
Delta IRANI score [(IRANI Prostatectomy – IRANI Biopsy)/IRANI Prostatectomy] | 45% (25–50%) | 50% (40–50%) | 32.5 (25–50%) | 0.7 |