Figure 5.

Functional avidity of human FRT-derived HSV-2-specific polyclonal CD8 T_RM from subject 15018 cervical biopsies from June (top rows) or September (lower row) samples. TCL were incubated with autologous EBV-LCL and dilutions of peptide. Insets list HSV-2 gene, AA numbers and sequence of peptide tested, and HLA restriction of epitope. T cell activation was measured by supernatant IFN-γ ELISA. Colored dots are duplicate raw data and gray bar is mean. Note varied X and Y axes. Some peptides were tested over an expanded concentration range. DSMO negative control <0.06 OD₄₅₀ for all assays.