Table 2.
Activation of FRT biopsy-derived T cells after exposure to HSV-2-loaded autologous moDC.
| PtID | biopsy date(s) | Biopsy site | |||
|---|---|---|---|---|---|
| Cervix | Skin | ||||
| CD3+ T cell phenotype | CD3+ T cell phenotype | ||||
| CD4+CD8- | CD8+CD4- | CD4+CD8- | CD8+CD4- | ||
| 9149 | 8/31/16 | 0.91 | 4.7 | 0.4 | 5.6 |
| 13497 | 11/2/2016 | 0.8 | 0 | 0.9 | 0 |
| 14655 | 10/31/2016 | 5.1 | 1.7 | 0 | 0 |
| 14887 | 10/27/2016 | 1.3 | 1 | 0.4 | 1.4 |
| 15018 | 6/27/2016 | 12 | 20.5 | 0 | 0 |
| 15018 | 9/28/2016 | 3.7 | 3.5 | 0 | 0 |
| 15052 | 5/5/2016 | ND2 | 0.3 | ND | ND |
| 15052 | 6/9/2016 | 0 | 2.4 | 0.8 | 2.5 |
| mean | 3.40 | 4.26 | 0.36 | 1.36 | |
| standard deviation | 4.20 | 6.75 | 0.38 | 2.1 | |
1Values are net percentage of biopsy-derived live T cells expressing CD137 for HSV-2-loaded DC minus mock virus-loaded DC. Net values of less than zero are reported as zero.
2ND indicates not done.