Demographics
|
Age, mean years (SD) |
30.8 (6.4) |
28.7 (7.4) |
0.13 |
68.6 (7.2) |
67.1 (7.0) |
0.32 |
Sex (% female) |
28.6% |
41.4% |
0.23 |
44.0% |
46.4% |
0.84 |
Education, mean years (SD) |
15.0 (3.8) |
17.2 (2.6) |
0.001 |
15.0 (5.6) |
16.7 (4.9) |
0.21 |
Partner status (% with partner) |
21.4% |
51.7% |
0.004 |
84.0% |
82.1% |
0.83 |
Country (% Spain) |
39.1% |
48.3% |
0.43 |
42.0% |
25.0% |
0.13 |
Specific disorder characteristics
|
Psychotropic medication |
|
Antipsychotic (%) |
89.3% |
0% |
|
4.0% |
0% |
|
Antidepressant (%) |
19.6% |
0% |
|
16.0% |
0% |
|
Acetylcholinesterase inhibitor or NDMA receptor antagonist (%) |
0% |
0% |
|
43.8% |
0% |
|
Benzodiazepines (%) |
10.7% |
0% |
|
6.3% |
7.1% |
|
Other psychotropics (%) |
14.3% |
0% |
|
2.1% |
3.6% |
|
Severity of disorder |
|
Schizophrenia severity |
|
|
|
|
|
|
Positive symptoms, mean PANSS (SD) |
11.0 (3.4) |
NA |
|
NA |
NA |
|
Negative symptoms, mean PANSS (SD) |
14.6 (6.2) |
NA |
|
NA |
NA |
|
AD severity, mean ADAS-Cog (SD) |
NA |
NA |
|
26.9 (7.2) |
NA |
|
Mood characteristics
|
Depression severity, mean QIDS-SR (SD) |
8.0 (5.3) |
2.1 (1.5) |
<0.001 |
4.1 (2.8) |
2.0 (1.3) |
<0.001 |
Anxiety severity, mean STAI (SD) |
43.5 (11.2) |
30.4 (5.9) |
<0.001 |
30.7 (8.2) |
27.5 (5.8) |
0.08 |
Mood state, PANAS |
|
|
|
|
|
|
Positive Affect, mean (SD) |
29.5 (6.6) |
37.5 (5.9) |
<0.001 |
32.5 (5.1) |
38.2 (6.1) |
<0.001 |
Negative Affect, mean (SD) |
18.7 (6.5) |
13.9 (3.0) |
<0.001 |
13.9 (4.6) |
12.7 (3.0) |
0.24 |