Table 3.
Univariate logistic analysis of the training group.
| Variable, n (%) | Training group (n = 1230) | Outcome | Statistical | P | |
|---|---|---|---|---|---|
| Survival (n = 628) | Death (n = 602) | ||||
| Age, years, mean ± SD | 61.92 ± 17.31 | 55.30 ± 17.78 | 68.83 ± 13.77 | t = −14.970 | <0.001 |
| Sex | χ 2 = 0.172 | 0.678 | |||
| Male | 700 (56.91) | 361 (57.48) | 339 (56.31) | ||
| Female | 530 (43.09) | 267 (42.52) | 263 (43.69) | ||
| SaO2, mean ± SD | 87.88 ± 14.06 | 88.34 ± 13.13 | 87.41 ± 14.97 | t = 1.160 | 0.246 |
| PaO2/FiO2, M (Q1, Q3) | 27.31 (16.52, 42.84) | 30.46 (18.17, 46.58) | 24.54 (15.00, 37.62) | Z = −5.321 | <0.001 |
| PLT, M (Q1, Q3) | 209.00 (145.00, 288.00) | 207.50 (149.00, 281.00) | 210.00 (137.00, 293.00) | Z = 0.162 | 0.871 |
| pH, mean ± SD | 7.34 ± 0.12 | 7.34 ± 0.12 | 7.34 ± 0.12 | t = 0.260 | 0.795 |
| Lactate, M (Q1, Q3) | 2.00 (1.30, 3.30) | 1.90 (1.30, 3.30) | 2.00 (1.40, 3.30) | Z = 1.014 | 0.311 |
| INR, M (Q1, Q3) | 1.30 (1.10, 1.50) | 1.20 (1.10, 1.40) | 1.30 (1.20, 1.70) | Z = 6.092 | <0.001 |
| Creatinine, M (Q1, Q3) | 1.00 (0.70, 1.40) | 0.90 (0.70, 1.20) | 1.10 (0.80, 1.60) | Z = 5.050 | <0.001 |
| Hematocrit, mean ± SD | 33.04 ± 6.28 | 33.64 ± 6.47 | 32.42 ± 6.02 | t = 3.440 | <0.001 |
| Hemoglobin, mean ± SD | 11.13 ± 2.15 | 11.39 ± 2.24 | 10.85 ± 2.02 | t = 4.470 | <0.001 |
| AST, M (Q1, Q3) | 44.00 (28.00, 98.00) | 45.00 (29.00, 95.00) | 43.00 (27.00, 104.00) | Z = −0.455 | 0.649 |
| ALT, M (Q1, Q3) | 31.00 (18.00, 72.00) | 30.00 (19.00, 64.00) | 31.00 (17.00, 88.00) | Z = 0.844 | 0.399 |
| TBIL | χ 2 = 14.059 | <0.001 | |||
| Normal | 744 (60.49) | 412 (65.61) | 332 (55.15) | ||
| Abnormal | 486 (39.51) | 216 (34.39) | 270 (44.85) | ||
| BUN | χ 2 = 26.937 | <0.001 | |||
| Normal | 1026 (83.41) | 490 (78.03) | 536 (89.04) | ||
| Abnormal | 204 (16.59) | 138 (21.97) | 66 (10.96) | ||
| WBC | χ 2 = 0.088 | 0.767 | |||
| Normal | 1032 (83.90) | 525 (83.60) | 507 (84.22) | ||
| Abnormal | 198 (16.10) | 103 (16.40) | 95 (15.78) | ||
| Potassium | χ 2 = 3.793 | 0.051 | |||
| Normal | 1029 (83.66) | 538 (85.67) | 491 (81.56) | ||
| Abnormal | 201 (16.34) | 90 (14.33) | 111 (18.44) | ||
| Sodium | χ 2 = 0.021 | 0.884 | |||
| Normal | 1112 (90.41) | 567 (90.29) | 545 (90.53) | ||
| Abnormal | 118 (9.59) | 61 (9.71) | 57 (9.47) | ||
| Bicarbonate | χ 2 = 1.028 | 0.311 | |||
| Normal | 1001 (81.38) | 518 (82.48) | 483 (80.23) | ||
| Abnormal | 229 (18.62) | 110 (17.52) | 119 (19.77) | ||
| MAP, mean ± SD | 84.74 ± 17.32 | 86.06 ± 17.74 | 83.38 ± 16.77 | t = 2.720 | 0.007 |
| ICU type | χ 2 = 1.743 | 0.187 | |||
| Medical ICU | 834 (67.80) | 415 (66.08) | 419 (69.60) | ||
| Others | 396 (32.20) | 213 (33.92) | 183 (30.40) | ||
| ARDS cause | χ 2 = 2.190 | 0.334 | |||
| Pneumonia | 109 (8.86) | 56 (8.92) | 53 (8.80) | ||
| Sepsis | 40 (3.25) | 25 (3.98) | 15 (2.49) | ||
| Others | 1081 (87.89) | 547 (87.10) | 534 (88.70) | ||
| Bicarbonate input | χ 2 = 9.770 | 0.002 | |||
| No | 1049 (85.28) | 555 (88.38) | 494 (82.06) | ||
| Yes | 181 (14.72) | 73 (11.62) | 108 (17.94) | ||
| Ventilation | χ 2 = 33.480 | <0.001 | |||
| No | 1058 (86.02) | 505 (80.41) | 553 (91.86) | ||
| Yes | 172 (13.98) | 123 (19.59) | 49 (8.14) | ||
| Ventilation time, M (Q1, Q3) | 8.00 (3.00, 15.00) | 8.00 (3.00, 15.00) | 7.00 (3.00, 15.00) | Z = 0.183 | 0.855 |
| SAPS II, M (Q1, Q3) | 38.00 (29.00, 48.00) | 32.50 (21.00, 41.00) | 43.00 (35.00, 53.00) | Z = 13.604 | <0.001 |
| GCS score, M (Q1, Q3) | 8.00 (4.00, 13.00) | 8.00 (3.00, 13.00) | 9.00 (5.00, 13.00) | Z = 1.529 | 0.126 |
| SOFA score, M (Q1, Q3) | 7.00 (4.00, 9.00) | 6.00 (3.00, 8.00) | 7.00 (5.00, 10.00) | Z = 6.820 | <0.001 |
| Immune function impairment | χ 2 = 30.088 | <0.001 | |||
| No | 868 (70.57) | 487 (77.55) | 381 (63.29) | ||
| Yes | 362 (29.43) | 141 (22.45) | 221 (36.71) | ||
| Heart failure | χ 2 = 69.255 | <0.001 | |||
| No | 860 (69.92) | 506 (80.57) | 354 (58.80) | ||
| Yes | 370 (30.08) | 122 (19.43) | 248 (41.20) | ||
| Renal failure | χ 2 = 76.323 | <0.001 | |||
| No | 816 (66.34) | 489 (77.87) | 327 (54.32) | ||
| Yes | 414 (33.66) | 139 (22.13) | 275 (45.68) | ||
| Respiratory rate, M (Q1, Q3) | 19.00 (14.00, 24.00) | 19.00 (14.00, 24.00) | 18.00 (14.00, 24.00) | Z = −1.590 | 0.112 |
| Heart rate, mean ± SD | 94.36 ± 21.49 | 95.36 ± 21.12 | 93.32 ± 21.83 | t = 1.660 | 0.097 |
Note. ICU: intensive care unit; ARDS: acute respiratory distress syndrome; AST: aspartate transaminase; ALT: alanine transaminase; INR: international normalized ratio; RBC: red blood cell; PLT: platelet; TBIL: total bilirubin; BUN: blood urea nitrogen; WBC: white blood cell; MAP: mean arterial pressure; SAPS II: Simplified Acute Physiology Score II; GCS: Glasgow Coma Scale; SOFA score: Sequential Organ Failure Assessment score.