Fig. 2.

Effects of CPC on the interaction between S protein (RBD) and ACE2, (A) Binding in the presence of CPC. The % binding of each sample was calculated based on the absorbance with 0% CPC (control). (B) Binding of CPC-treated RBD with ACE2. “Interference” indicates the influence of a neutralized CPC solution on binding of RBD to ACE2. After neutralization, CPC was incubated in ACE2-coated wells for 1 h and the ACE2-RBD binding assay was performed. (C) Binding of RBD with 0.3% CPC-treated ACE2. The assay diluent was tested similarly and is indicated as CPC(-). Data are shown as means± S.E.M. (n = 3). *p < 0.05, * *p < 0.001 vs. untreated control by two-sided Dunnett test.