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. 2022 Mar 31;13:847760. doi: 10.3389/fendo.2022.847760

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Copyright © 2022 Hu, Zeng, Ge, Wang, Qin, Zhang, Jiang and Liu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Immune microenvironment analysis in PC patients with high and low S100A6 expression. (A) Comparison of ESTIMATE Score, Stromal score, and Immune score between S100A6-high and S100A6-low groups by ssGSEA algorithm. (B) Relationship of S100A6 expression and RNAss, DNAss, Stromal Score, and Immune Score. (C) Comparison of immune cell subsets, (D) immune-related functions, (E) immune checkpoints between S100A6-high and S100A6-low groups. PC, pancreatic cancer; ssGSEA, single-sample Gene Set Enrichment Analysis. ns, no significance, ^∗p < 0.05, ^∗∗p < 0.01, and ^∗∗∗p < 0.001.