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CYP3A5, tacrolimus dose and IPV
| CYP3A5 nonexpressor, n = 59 | CYP3A5 expressor, n = 21 | |||||
|---|---|---|---|---|---|---|
| IR‐tacrolimus | ER‐tacrolimus | LCP‐tacrolimus | IR‐tacrolimus | ER‐tacrolimus | LCP‐tacrolimus | |
| Tacrolimus daily dose, mg | 3.7 (1.8) | 4.0 (2.1) | 2.6 (1.4) | 9.3 (5.7) | 9.4 (6.0) | 5.9 (4.6) |
| Tacrolimus IPV, % | 16.6 (10.3) | 15.6 (9.5) | 18.1 (7.1) | 14.7 (7.8) | 16.0 (9.0) | 19.4 (6.4) |
Results are expressed as mean (SD).
Abbreviations: ER, extended release; IR, immediate release; IPV, intrapatient variability; LCP, LifeCyclePharma.
