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. 2022 Apr 13;2(4):100118. doi: 10.1016/j.xgen.2022.100118
REAGENT or RESOURCE SOURCE IDENTIFIER
Deposited data

The FinnGen data may be accessed through Finnish Biobanks’ FinBB portal - http://www.finnbb.fi
GWAS genotype data of BioBank Japan are available at the National Bioscience Database Center Human Database Nagai et al., 2017 Research ID: hum0014; https://humandbs.biosciencedbc.jp/en/hum0014-v21
UK Biobank data are available through a procedure described at http://www.ukbiobank.ac.uk/using-the-resource/ Bycroft et al., 2018 http://www.ukbiobank.ac.uk/using-the-resource/
The Trøndelag Health Study (HUNT). The HUNT data may be accessed by application to the HUNT Research Centre. Krokstad et al., 2013 https://www.ntnu.edu/hunt
De-identified data of the MGB Biobank that supports this study is available from the MGB Biobank portal. Restrictions apply to the availability of these data, which are available to MGB-affiliated researchers via a formal application. Karlson et al., 2016 https://biobank.partners.org/
Estonian Biobank. Researchers interested in Estonian Biobank can request the access at https://www.geenivaramu.ee/en/access-biobank Leitsalu et al., 2015 https://www.geenivaramu.ee/en/access-biobank
PGS Catalog/LDpred polygenic risk scores This paper https://www.pgscatalog.org/
PGS002241–PGS002244
PGS Catalog/PRS-CS polygenic risk score for prostate cancer This paper https://www.pgscatalog.org/
PGS002240
PGS Catalog/PRS-CS polygenic risk score for breast cancer Mars et al., 2020 https://www.pgscatalog.org/
PGS000335
PGS Catalog/PRS-CS polygenic risk score for coronary artery disease and type 2 diabetes Tamlander et al., 2022 https://www.pgscatalog.org/
PGS001780, PGS001781

Software and algorithms

PRS-CS (version Sep 10, 2020) Ge et al., 2019 https://github.com/getian107/PRScs
PLINK v2.00a2.3LM Chang et al., 2015 https://www.cog-genomics.org/plink/2.0/
STEROID 0.1 - https://genomics.ut.ee/en/tools/steroid
Eagle v2.3.5 Loh P-R et al. 2016 https://alkesgroup.broadinstitute.org/Eagle/
R statistical programming v3.2.0 or later - https://www.r-project.org/
LDpred v1.0.7 Vilhjálmsson et al. 2015 https://github.com/bvilhjal/ldpred

Other

PRS-CS pipeline - https://github.com/FINNGEN/CS-PRS-pipeline
Project code This paper https://doi.org/10.5281/zenodo.6203211