Table 3.
PL composition of SARS-CoV2, compared with rat liver membranes, reproduced from Vance (35) and Van Meer (9)
| Vance (35) |
|||||||||
|---|---|---|---|---|---|---|---|---|---|
| Lipid | ER | Mito inner | Mito outer | Lysosomes | Nuclei | Golgi | Plasma membrane | Vero | A549 |
| PC | 57 | 41 | 49 | 42 | 52 | 45 | 43 | 61 | 40 |
| PE | 21 | 38 | 34 | 21 | 25 | 17 | 21 | 19 | 23 |
| SM | 4 | 2 | 2 | 16 | 6 | 12 | 23 | 0.024 | 0.009 |
| PI | 9 | 2 | 9 | 6 | 4 | 9 | 7 | 18 | 37 |
| PS | 4 | 1 | 1 | 1 | 6 | 4 | 4 | 0.013 | 0.005 |
| CL | 0 | 16 | 5 | 0 | 0 | 0 | 0 | ||
| Other | 5 | <1 | <1 | 14 | 7 | 13 | 2 | 1.75 | 0.33 |
| Chol/PL molar ratio |
0.07 |
0.06 |
0.06 |
0.49 |
0.15 |
0.76 |
0.0006 |
0.0005 |
|
| Van Meer (9) |
|||||||||
| PC | 58 | 50 | 39 | ||||||
| PE | 22 | 20 | 23 | ||||||
| SM | 3 | 8 | 16 | ||||||
| PI | 10 | 12 | 8 | ||||||
| PS | 3 | 6 | 9 | ||||||
| Chol/PL molar ratio | 0.08 | 0.16 | 0.35 | ||||||
Approximate PL content is given as percent of total lipid phosphorus, data are averaged from several sources in both studies, as described.