Table 2.
Age of primary breast cancer cases and characteristics of census tracts where they resided at time of diagnosis, by race/ethnicity and subtype, 2006–2015 (n = 118,381)
| Overall | NH Black | NH White | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Both subtypes (n=118,381) | Luminal A (n=102,853 (86.9%)) | TNBC (n=15,528 (13.1%)) | Both subtypes (n=11,063) | Luminal A (n=8,170 (73.8%)) | TNBC (n=2,893 (26.2%)) | Both subtypes (n=107,318) | Luminal A (n=94,683 (88.2%)) | TNBC (n=12,635 (11.8%)) | |
| Age (median (IQR)) | 64 (54, 73) | 64 (54, 74) | 60 (51, 71) | 60 (51, 70) | 61 (52, 71) | 58 (49, 67) | 64 (54, 74) | 65 (55, 74) | 61 (51, 71) |
| Racial bias index (median (IQR))a | 2.2 (1.5, 3.4) | 2.2 (1.5, 3.5) | 2.2 (1.5, 3.4) | 2.0 (1.4, 2.9) | 2.0 (1.4, 2.9) | 2.0 (1.4, 3.0) | 2.3 (1.5, 3.5) | 2.3 (1.5, 3.5) | 2.2 (1.5, 3.5) |
| Q1 (%) | 17.7 | 17.7 | 18.2 | 22.0 | 22.1 | 21.7 | 17.3 | 17.3 | 17.3 |
| Q2 (%) | 19.9 | 19.8 | 20.5 | 23.0 | 22.9 | 23.2 | 19.5 | 19.5 | 19.9 |
| Q3 (%) | 20.2 | 20.1 | 20.8 | 21.5 | 21.4 | 21.6 | 20.0 | 20.0 | 20.6 |
| Q4 (%) | 21.0 | 21.1 | 20.5 | 19.2 | 19.1 | 19.4 | 21.2 | 21.3 | 20.8 |
| Q5 (%) | 21.2 | 21.4 | 20.0 | 14.3 | 14.4 | 14.1 | 21.9 | 22.0 | 21.4 |
|
SES index (median (IQR))b |
0.5 (−0.2, 1.1) | 0.5 (−0.2, 1.1) | 0.3 (−0.4, 1.0) | −0.4 (−1.0, 0.3) | −0.4 (−1.0, 0.4) | −0.4 (−1.0, 0.3) | 0.6 (−0.1, 1.2) | 0.6 (−0.1, 1.2) | 0.5 (−0.2, 1.1) |
| Neighborhood stability (median (IQR))c | 86.4 (81.0, 90.7) | 86.5 (81.0, 90.8) | 86.1 (80.5, 90.5) | 85.7 (79.9, 90.3) | 85.8 (80.0, 90.5) | 85.4 (79.5, 90.1) | 86.5 (81.1, 90.8) | 86.6 (81.1, 90.8) | 86.3 (80.8, 90.5) |
Data restricted to invasive breast cancer cases for whom census tract and tumor subtype information were known (Luminal A or TNBC), and who resided in California MSAs at time of diagnosis (n = 118,381)
aRacial Bias Index = census-tract average odds of a mortgage denial for a Black applicant as compared to a White applicant, adjusting for individual sex, and the ratio of the loan amount to the applicant's gross annual income (data from Home Mortgage Disclosure Act, 2007–2013. (https://www.ffiec.gov/hmda/)); Q1: [0.3, 1.3), Q2: [1.3, 1.9), Q3: [1.9, 2.5), Q4: [2.5, 3.8), Q5: [3.8, 86.2]
bYang Neighborhood SES Index = validated, census-tract level composite of median school years, percentage of high school graduates, proportion with a blue collar job, proportion older than 16 in the workforce without a job, median household income, proportion below 200% of the poverty level, median rent, and median house value, derived from 2007 to 2011 American Community Survey [5, 36, 37]
cNeighborhood stability = census tract percent of residents who lived the same house one year ago on 2007–2011 American Community Survey [37]
Abbreviations: HR hormone receptor status, HER2 human epidermal growth factor receptor, SES socioeconomic status, SD standard deviation, IQR interquartile range