Table 1.
Number of Unique Formulations by Molecule Types of Active Pharmaceutical Ingredients and Dosage Forms
| Molecule type | Powder for recon. | Liquid | Solid1 | Semisolid2 | Total |
|---|---|---|---|---|---|
| Antibody conjugate3 | 6 | 2 | 8 | ||
| Cytokine and growth factor | 20 | 62 | 1 | 83 | |
| Enzyme | 17 | 25 | 5 | 1 | 48 |
| Monoclonal antibody4 | 26 | 92 | 118 | ||
| Polypeptide hormone | 48 | 55 | 6 | 109 | |
| Pulmonary surfactant | 3 | 3 | |||
| Recombinant fusion protein | 8 | 10 | 18 | ||
| Toxin | 9 | 1 | 10 | ||
| Total | 134 | 250 | 11 | 2 | 397 |
1Solid dosage forms include tablet, capsule and powder for inhalation
2Semisolid dosage forms include gel and ointment
3Antibody conjugate molecule types include antibody-drug conjugates, antibody linker-chelator conjugate, and antibody-toxin conjugate
4Includes antibody fragments and bispecifics