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. Author manuscript; available in PMC: 2023 Apr 15.
Published before final editing as: Eur J Cancer. 2021 Oct 15;158:99–110. doi: 10.1016/j.ejca.2021.09.010

Table 3:

Fixed-effect cause-specific proportional hazards regression analysis for VTE events within two years pre-and post-immune checkpoint inhibitors

Entire Cohort (n=2854) Patients who are alive at 6 months’ post immune checkpoint inhibitors (n=2287) Patients who are alive at 1 year post immune checkpoint inhibitors (n=2077) Patients who are alive and have not been lost to follow up at 2 years post immune checkpoint inhibitors (n=754)
Hazard ratio (95% confidence Interval) P value Hazard ratio (95% confidence Interval) P value Hazard ratio (95% confidence Interval) P value Hazard ratio (95% confidence Interval) P value
Deep Vein Thrombosis 5.70 (3.79, 8.59) <0.001 4.58 (2.99, 7.00) <0.001 4.04 (2.61, 6.26) <0.001 5.73 (3.13, 9.92) <0.001
Pulmonary Embolism 4.75 (3.20, 7.10) <0.001 3.76 (2.50, 5.66) <0.001 3.18 (2.08, 4.86) <0.001 4.47 (2.64, 7.56) <0.001
Venous Thromboembolism 4.98 (3.65, 6.79) <0.001 3.98 (2.89, 5.48) <0.001 3.49 (2.51, 4.86) <0.001 4.89 (3.26, 7.35) <0.001