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. Author manuscript; available in PMC: 2023 Apr 15.
Published before final editing as: Eur J Cancer. 2021 Oct 15;158:99–110. doi: 10.1016/j.ejca.2021.09.010

Table 4:

Multivariate Cox regression analysis for association between risk factors and a VTE event post ICI initiation comparing patients who developed VTE while on an ICI (n=259) to those who did not have a VTE event (n=2610)

Hazard Ratio (95% confidence interval) P value
Age >65 0.75 (0.58, 0.98) 0.03
History of hypertension 1.37 (1.06, 1.77) 0.015
History of smoking 1.24 (0.89, 1.73) 0.21
VTE prior to ICI 1.42 (0.99, 2.06) 0.06
Melanoma 0.59 (0.41, 0.85) 0.004
Non-small cell lung cancer 1.10 (0.81, 1.51) 0.54
Renal and genitourinary 1.47 (0.92, 2.35) 0.10
Therapeutic anticoagulation at initiation of ICI 1.04 (0.67, 1.63) 0.86
Khorana Risk Score ≥2 1.54 (1.14, 2.09) 0.005