TABLE 1.
MICs of β-lactams for the Ec GCE clinical strain, E. coli MC4100(pGC1), E. coli TG1, and E. coli TG1(pGC-2)
| Antibiotica | MIC (μg/ml) for:
|
|||
|---|---|---|---|---|
| Ec GCE (produces TEM-1 + FOX-4) | MC4100 (pGC1) (produces FOX-4) | TG-1 | TG1 (pGC-2) (produces FOX-4) | |
| Ampicillin | >1,024 | 64 | 4 | 256 |
| Ampicillin + clavulanate | 64 | 64 | 4 | 256 |
| Ticarcillin | >1,024 | 64 | 4 | 512 |
| Temocillin | 4 | 2 | 2 | 16 |
| Cefoxitin | 512 | 256 | 4 | >512 |
| Cefoxitin + clavulanate | 512 | 256 | 4 | >512 |
| Cefotetan | 64 | 32 | 0.2 | 128 |
| Moxalactam | 8 | 4 | 0.06 | 32 |
| Moxalactam + clavulanate | 8 | 4 | 0.06 | 32 |
| Cefotaxime | 32 | 16 | 0.03 | 64 |
| Cefotaxime + clavulanate | 32 | 16 | 0.03 | 64 |
| Ceftazidime | 128 | 64 | 0.12 | >128 |
| Ceftazidime + clavulanate | 128 | 64 | 0.12 | >128 |
| Cefepime | 1 | 0.5 | 0.03 | 2 |
| Aztreonam | 16 | 8 | 0.03 | 64 |
| Imipenem | 0.12 | 0.25 | 0.12 | 0.5 |
| Meropenem | 0.03 | 0.03 | 0.03 | 0.12 |
a
Clavulanate was used at 4 μg/ml.