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. 2022 Apr 1;13:857242. doi: 10.3389/fimmu.2022.857242

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Copyright © 2022 Zhang, Qin, Song, Yuan, Hu, Chen and Li

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Gut microbiota analysis. (A) Non-metric dimensional scaling (NMDS) plots; (B) ANOSIM analysis of the significance of separation between the NC, CIS, and AO groups; (C) relative abundance of the top 10 phyla; (D) relative abundance of top ten genus; (E) relative abundance of top ten species; n=10 for the AO and NC groups, n=9 for the CIS group (one mouse in the CIS group died while collecting feces). NC, normal control; CIS, cisplatin; AO, cisplatin with alginate oligosaccharides (*p < 0.05, **p < 0.01; ↑, upregulation; ↓, downregulation).