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The median ratios of the minimal inhibitory concentration (MIC) from 24 to 0 h are depicted for E. coli isolates for all three regimens and all tested concentrations. A ratio at 1 or below indicates no change of the MIC. Ratios above 2 indicate an emergence of resistance.
| E. coli isolates | |||||||
|---|---|---|---|---|---|---|---|
| Median ratio 24h/0 h | 32×MIC | 16×MIC | 8×MIC | 4×MIC | 2×MIC | 1×MIC | 0.5×MIC |
| 40% | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 2 × 20% | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 3 × 13.3% | 0.5 | 1 | 0.75 | 0.75 | 0.5 | 0.5 | 0.5 |
