TABLE 2.

1-position modification of Matrine.

Name of matrine derivative	Basic structure of derivatives	R Substituent structure	Structure of matrine derivatives	Pharmacological activity	Refrences
Matrine acetylsalicylate				Anti-inflammation and pain relief	Fu et al. (2011)
Matrine 3-nitrooxymethyl benzoate				Anti-myocardial ischemia	Li et al. (2015)
Matrine [GaCl4] complex				Anti tumor	Chen et al. (2011)
Matrine [AuCl4] complex				Anti tumor	Chen et al. (2011)