Table 1.
Demographic and clinical data of subjects from whom biopsies were obtained.
| Healthy (n = 20) | Asthmatics (n = 16) | |
|---|---|---|
| Age (years) a | 63.7 (46–78) | 52.4 (26–79) |
| Gender (female) (%) | 8 (40.0) | 6 (37.5) |
| Atopy (%) | 0 (0.0) | 3 (18.8) |
| Smoking history | ||
| Current (%) | 4 (20.0) | 4 (25.0) |
| Ex-smoker (%) | 4 (20.0) | 7 (43.7) |
| Non-smoker (%) | 12 (60.0) | 5 (31.3) |
| Bronchiectasis (%) | NA | 2 (12.5) |
| Chronic bronchitis (%) | NA | 2 (12.5) |
| Immunological disease (%) | 0 (0.0) | 3 (18.8) |
| Cardiopathy (%) | 4 (20.0) | 2 (12.5) |
| Blood cell counts (%) | ||
| Leukocytes (mean ± SD) | 13.7 ± 4.9 | 9.2 ± 3.8 b |
| Neutrophils (mean ± SD) | 80.6 ± 6.1 | 71.4 ± 16.2 b |
| Lymphocytes (mean ± SD) | 10.7 ± 3.9 | 18.2 ± 12.7 b |
| Monocytes (mean ± SD) | 7.7 ± 2.6 | 8.4 ± 2.9 |
| Eosinophils (mean ± SD) | 0.8 ± 0.8 | 1.6 ± 1.9 |
| Basophils (mean ± SD) | 0.3 ± 0.2 | 0.4 ± 0.4 |
| Hematocrit (mean ± SD) | 35.1 ± 6.1 | 39.5 ± 5.6 b |
| Platelets (mean ± SD) | 190.1 ± 74.2 | 250.4 ± 89.8 b |
| FEV1% (mean ± SD) | NA | 69.1 ± 31.1 |
| FVC% (mean ± SD) | NA | 66.8 ± 28.2 |
| FEV1/FVC% (mean ± SD) | NA | 75.0 ± 15.4 |
| Inhaled/systemic corticosteroid treatment (%) | NA | 9 (56.3) |
a
Average (range).
b
p < 0.05.
NA, non-available; SD, standard deviation.