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. 2022 Mar 7;298(4):101770. doi: 10.1016/j.jbc.2022.101770

Table 1.

Metal composition comparison of DMEM and Opti-MEM determined by inductively coupled plasma MS

Analyte Mg Al Ca Cr Fe Mn Co Ni Cu Zn
Detection limits 0.002 0.0002 0.031 0.00005 0.0037 0.00003 0.00003 0.00006 0.00003 0.00008
Units ppm ppm ppm ppm ppm ppm ppm ppm ppm ppm
Opti-MEM 24.475 ± 3.09 0.004 ± 0.002 40.958 ± 5.27 0.060 ± 0.03 0.040 ± 0.00 0.001 ± 0.00 0.046 ± 0.01 0.001 ± 0.00 0.037 ± 0.02 0.075 ± 0.01
DMEM 19.580 ± 1.18 0.002 ± 0.00 71.99 ± 11.11 0.084 ± 0.04 <DL 0.001 ± 0.00 0.001 ± 0.00 0.002 ± 0.00 0.055 ± 0.02 0.025 ± 0.02
DMEM + ZnCl2 17.407 0.006 72.361 0.041 <DL 0.001 0.000 0.002 0.027 0.108
DMEM + transferrin 19.006 0.004 71.206 0.04 0.026 0.002 0.000 0.002 0.027 0.034
DMEM + cbl 19.287 ± 0.29 0.002 61.032 0.056 <DL 0.001 0.035 ± 0.01 0.001 0.036 ± 0.01 0.023 ± 0.00

<DL, below detection limit.