Table 1.
The correlation between HH signaling proteins and the prognosis of lung cancer.
| Sample | Pathology subtype | TNM | Method | Gene or Protein | Prognostic marker | Reference |
|---|---|---|---|---|---|---|
| 167 | LSCC, LAC | I-IV | IHC | SHH | SHH | (89) |
| 403 | LSCC, LAC | I-IV | IHC | Gli3FL, Gli3TR | Gli3TR | (90) |
| 40 | LSCC, LAC | I-II | IHC | SHH, Gli1, LYVE-1, VEGF-D | SHH, Gli1, LYVE-1 | (91) |
| 248 | LSCC, LAC | I-II | IHC | SHH, Ptch1, Smo, Gli1, Gli2, ALDH1A1 | NO | (92) |
| 81 | LSCC, LAC | I-IV | IHC | SHH, Ptch1, Smo, Gli1, | NO | (93) |
| 101 | LSCC | I-III | IHC | Gli1, LSD1, CD44, Sox9, Gli1, Sox2 | Gli1 | (94) |
| 102 | LAC | II-IV | qPCR | Gli1mRNA, Gli2mRNA, Gli3mRNA | Gli1mRNA | (95) |
| 166 | LAC | I-IV | IHC | SHH, Gli1, Gli2, Gli3, ABCG2 | NO | (96) |
| 12 | SCLC | III-IV | qPCR | Gli1mRNA | Gli1mRNA | (97) |
| 36 | SCLC | III-IV | IHC | SHH, Gli1, Ptch1, Smo | SHH | (98) |