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. 2022 Apr 1;12:865121. doi: 10.3389/fonc.2022.865121

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Copyright © 2022 Li, Dong, Wu, Wang, Jin, Chen, Huang, Huang and Yao

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) The presence and abundance of tumor-infiltrating CD4⁺ TILs as assessed with IHC staining between representing NAC non-effectual patients (P1, P2, P3) and NAC effectual patients (P4, P5, P6). Scale bars, 50 μm. (B) The presence and abundance of tumor-infiltrating CD8⁺ TILs as assessed with IHC staining between representing NAC non-effectual patients (L1, L2, L3) and NAC effectual patients (L4, L5, L6). Scale bars, 50 μm. IHC, immunohistochemistry. Data show means ± s.d. ** denotes p < 0.01 by Student’s t-test. *** denotes p < 0.001 by Student’s t test.