Table 3.

Effects of Equisetum arvenese methanolic extract (EE) on total number of Leydig and Sertoli cells in streptozotocin-induced diabetes in mice

Parameters	Control-sham	Diabetic	Diabetic + 250 mg kg -1 EE ‎	Diabetic + 500 mg kg -1 EE
Leydig cells in 1.00 mm 2	70.60 ± 5.02	52.20 ± 4.81a	67.20 ± 5.58b	66.20 ± 8.92b
Hypertrophic Leydig cells in 1.00 mm 2	3.52 ± 1.04	26.12 ± 1.32a	18.24 ± 1.10b	23.40 ± 1.42bc
Percentage of hypertrophic Leydig cells	4.98 ± 1.47	50.03 ± 2.53a	27.14 ± 1.64b	35.34 ± 2.15bc
Sertoli cells per tubule section	20.80 ± 1.48	12.60 ± 1.51a	18.20 ± 1.78b	19.80 ± 2.16b

^abc indicate significant difference compared to the control-sham group, diabetic group, and diabetic + 250 mg kg ^-1 extract group respectively at p < 0.05.