表 2.

多种突变株出现TRS基序突变

TRS motif mutations in several SARS-CoV-2 variants

Position/Wild	GISAID ID	Collection date	Mutant	Strain
The first column is the position of the nucleotide residue in the SARS-CoV-2 genome (GenBank: MN908947.3) and its wild type; The second column is the identifier of the record in the GISAID database; The third column is the sample collection date; The fourth column is the mutant of the TRS motif ACGAAC in the TRS- L (the mutated nucleotide residue is highlighted); The fifth column is the classification of the virus according to GISAID. EPI_ISL_2508633 is defined as the reference genome of the Delta variant with TRS motif mutation. M is A or C; S is G or C; Y is T or C; R is A or G; and W is T or A.
71C	EPI_ISL_1229164	2021/3/4	A<span style="background:#ffd700">M</span>GAAC	B.1.524
	EPI_ISL_1489724	2021/3/23	A<span style="background:#ffd700">S</span>GAAC	B.1.1.7
	EPI_ISL_2349776	2021/5/5	A<span style="background:#ffd700">M</span>GAAC	B.1.1.7
	EPI_ISL_2508657	2021/5/14	A<span style="background:#ffd700">M</span>GAAC	B.1.617.2
	EPI_ISL_2508861	2021/5/22	A<span style="background:#ffd700">Y</span>GAAC	B.1.617.2
72G	EPI_ISL_462431	2020/3/21	AC<span style="background:#ffd700">R</span>AAC	B.1.1
	EPI_ISL_483591	2020/5/2	AC<span style="background:#ffd700">R</span>AAC	B.6.6
	EPI_ISL_1816969	2021/4/23	AC<span style="background:#ffd700">R</span>AAC	B.1.617.2
	EPI_ISL_2349852	2021/5/11	AC<span style="background:#ffd700">R</span>AAC	B.1.617.2
	EPI_ISL_2508633	2021/5/16	AC<span style="background:#ffd700">A</span>AAC	B.1.617.2
	EPI_ISL_2508830	2021/5/20	AC<span style="background:#ffd700">R</span>AAC	B.1.617.2
	EPI_ISL_2508981	2021/5/27	AC<span style="background:#ffd700">R</span>AAC	B.1.617.2
73A	EPI_ISL_2508907	2021/5/24	ACG<span style="background:#ffd700">W</span>AC	B.1.617.2
75C	EPI_ISL_500540	2020/6/22	ACGAA<span style="background:#ffd700">T</span>	B.6.6