TABLE 2.
MNI coordinates (in mm) of local maxima in regions of interest for which BMI was negatively correlated with intrinsic functional connectivity with each seed at rest.
Seed | Cluster extent (p-value) | Region of interest | Hemisphere | Local maxima z-score | x | y | z |
Hippocampus | 773 (0.01) | ||||||
Dorsolateral PFC | Left | 4.26 | −30 | 56 | 12 | ||
Dorsolateral PFC | Left | 3.68 | −26 | 46 | 14 | ||
Dorsolateral PFC | Left | 3.54 | −28 | 46 | 24 | ||
Ventrolateral PFC | Left | 3.10 | −34 | 62 | 2 | ||
Amygdala | 753 (0.02) | ||||||
Superior Frontal Gyrus | Right | 3.9 | 18 | 58 | 30 | ||
Superior Frontal Gyrus | Right | 3.63 | 20 | 54 | 32 | ||
Dorsolateral PFC | Right | 3.48 | 28 | 40 | 30 | ||
Dorsal ACC | Right | 3.23 | 10 | 36 | 26 | ||
Dorsolateral PFC | Right | 2.92 | 28 | 52 | 24 |
Regions met a cluster-defining threshold of z > 2.3 and p < 0.05. Cluster extent is in voxels. The first coordinate listed under each cluster describes the location of the highest local maximum within the cluster. Additional regions with local maxima within the same cluster are listed following the strongest local maximum for that cluster. MNI, Montreal Neurological Institute; BMI, body mass index; PFC, prefrontal cortex; ACC, anterior cingulate cortex.