Table 1. Baseline characteristics of patients.
| Characteristics | Control (N=20) | CAVD (N=20) | P value |
|---|---|---|---|
| Age (years) | 49.80±8.20 | 54.15±8.01 | 0.098 |
| BMI (kg/m2) | 22.07±2.45 | 23.91±3.36 | 0.055 |
| Male, n (%) | 5 [25] | 16 [80] | <0.0001 |
| Smoking, n (%) | 2 [10] | 10 [50] | 0.006 |
| Diabetes mellitus, n (%) | 1 [5] | 1 [5] | 1.000 |
| Hypertension, n (%) | 6 [30] | 8 [40] | 0.507 |
| Coronary artery disease, n (%) | 2 [10] | 5 [25] | 0.405 |
| TC (mmol/L) | 4.25±0.93 | 4.53±1.54 | 0.484 |
| TG (mmol/L) | 1.11±0.33 | 2.22±4.87 | 0.316 |
| HDL-C (mmol/L) | 1.37±0.35 | 1.20±0.31 | 0.143 |
| LDL-C (mmol/L) | 2.54±0.86 | 2.67±0.79 | 0.617 |
| FBG (mmol/L) | 4.57±0.51 | 4.75±1.05 | 0.492 |
| Hb (g/L) | 127.90±16.01 | 131.2±16.38 | 0.523 |
| Ca2+ (mmol/L) | 2.22±0.11 | 2.20±0.12 | 0.526 |
| P3+ (mmol/L) | 1.01±0.21 | 1.04±0.11 | 0.651 |
| Gal-3 (ng/mL) | 7.63±2.50 | 9.82±2.58 | <0.05 |
| Transvalvular peak velocity (m/s) | 1.25±0.21 | 3.87±1.50 | <0.0001 |
| IVS (cm) | 0.92±0.16 | 1.31±0.29 | <0.0001 |
| LVEF (%) | 64.65±3.80 | 56.65±9.06 | 0.001 |
| LVEDD (cm) | 4.54±0.46 | 5.69±0.69 | <0.0001 |
CAVD, calcific aortic valve disease; BMI, body mass index; TC, total cholesterol; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; FBG, fasting blood glucose; Hb, hemoglobin; Gal-3, galectin-3; IVS, interventricular septal thickness; LVEF, left ventricular ejection fraction; LVEDD, left ventricular end-diastolic diameter.