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Approaches to encapsulate exosomes in hydrogels: (A) Combining the exosomes with polymers followed by the addition of crosslinkers to induce gelation. (B) Physical incorporation of the hydrogels, or the “breathing” technique. (C) Mixing of the exosomes with both the polymers in solution and crosslinkers simultaneously (Khayambashi et al., 2021). Copyright 2021, MDPI, Basel, Switzerland.
