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. 2022 Mar 19;3(4):100309. doi: 10.1016/j.jtocrr.2022.100309

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© 2022 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Efficacy analysis of initial ICI versus ICI rechallenge. (A) Overall response rates of initial ICI versus ICI rechallenge in studies with related information. (B) Pooled OR of overall response (CR/PR) in ICI rechallenge versus initial ICI. Lower OR represents lower incidence of overall response. (C) Disease control rates of initial ICI versus ICI rechallenge in studies with related information. (D) Pooled OR of disease control (CR/PR/stable disease) in ICI rechallenge versus initial ICI. Lower OR represents lower disease control rate. CI, confidence interval; CR, complete response; ICI, immune checkpoint inhibitor; M-H, Mantel–Haenszel; PR, partial response.