Table 1.

A summary of multiomics studies including data source, enabling technologies, and insights created for neuroimmunologys.

Study	-Omic Approach	Data Source	Enabling Technologies	Application in Neuroimmunology
Costantino et al, 201739	Genomics	Genes	DNA microarray	Genome-wide association study from 906 subjects, including 486 with spondyloarthritis (SpA), revealed an association of SpA with MAPK14
Bydon et al, 20202	Transcriptomics	RNA transcripts	RNA sequencing (RNA-seq)	Transcriptomics data from intervertebral disc samples showed immune signaling pathways were upregulated in DDD
Ma et al, 20214	Proteomics	Proteins	Matrix-assisted laser desorption/ionization time of flight (MALDI-TOF)	A computational analysis of protein-protein interactions in GBM cell lines identified opportunities to strategically improve immunotherapy design
Valentin-Guillama et al, 20185	Metabolomics	Small molecules and metabolites	Mass spectrometry, high performance liquid chromatography (HPLC)	Metabolomic data from gp120 treated glioma cells shows that HIV-1 can promote proliferation and activation of glycolysis, resulting in increased protein synthesis