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. 2022 Mar;10(6):291. doi: 10.21037/atm-22-685

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2022 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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JPTGY treatment alters the protein expression levels of biomarkers of BAT and WAT in mice after treatment with JPTGY. (A) Protein levels of the BAT biomarkers PGC-1α and UCP-1; (B) protein levels of WAT biomarkers, including AGT, PSTA, and EDNRA, in abdominal adipose tissue. The relative protein levels were calculated and are presented in histograms. *P<0.05 vs. control; ^#P<0.05 vs. obesity. JPTGY, Jian Pi Tiao Gan Yin; WAT, white adipose tissue; BAT, brown adipose tissue; PGC-1α, peroxisome proliferator-activated receptor gamma coactivator-1-alpha; UCP-1, uncoupling protein-1; AGT, angiotensinogen; PSTA, primary subtalar arthrodesis; EDNRA, endothelin receptor type A.