Table 3. The docking of the core targets with active compounds.

Molecule ID	Target	PDB ID	Binding energy (kcal/mol)
MOL008998	CREBBP	7JFM	−8.6
MOL000953	CREBBP		−7.3
MOL000358	CREBBP		−7.8
MOL001645	CREBBP		−4.3
MOL011169	CREBBP		−7.7
MOL001439	CREBBP		−4.7
MOL008999	CREBBP		−5.9
MOL001645	EP300	6V90	−3.8
MOL008999	EP300		−5.6
MOL000953	EGF	3NJP	−4.4
MOL000358	EGF		−6.7
MOL008998	CAT	1QQW	−9.2
MOL000953	CAT		−6.2
MOL001645	CAT		−2.6
MOL011169	CAT		−4.1
MOL001439	CAT		−2.8
MOL008999	CAT		−6.3

PDB, Protein Data Bank; CREBBP, CREB binding protein; EP300, E1A binding protein P300; EGF, epidermal growth factor; CAT, catalase.