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Induction of apoptosis of MCF-7R cells by metformin (Met). Flow cytometry was used to visualize the apoptosis of MCF-7R cells following processing with different drugs [5 mM Met, 1 µM 4-hydroxy tamoxifen (OHT) and 20 nM rapamycin (RAPA)] for 48 h. **, P<0.01 vs. control (without any treatment). Outcomes are given as mean ± SD of three independent assessments (n≥3).
