Table 2. Transition probability among different states.

Transition probability	1st cycle			2nd cycle
	PER + AEDs	AEDs		PER + AEDs	AEDs
<50% response rate	0.508	0.690		0.380	0.333
50–74% response rate	0.189	0.190		0.212	0.181
75–99% response rate	0.161	0.030		0.215	0.375
Seizure free rate	0.142	0.090		0.193	0.111

AEDs refer to the maintenance of conventional therapy. AED, antiepileptic drug; PER, perampanel.