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. 2022 Mar;10(6):304. doi: 10.21037/atm-22-556

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2022 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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DBH-AS1 expression is reduced in PC and correlates with worse survival outcomes. (A) GEPIA data revealed DBH-AS1 downregulation in PC. (B) qPCR analysis of DBH-AS1 levels in PC cell lines. (C) qPCR analysis of DBH-AS1 levels in 156 individuals with PC were collected from individuals with PC. (D) Kaplan-Meier analysis of the OS of 156 patients with PC. (E) Kaplan-Meier analysis of the OS of 176 patients with PC, sourced from the GEPIA database. (B,C) t-test; (D,E) log-rank test. Data are means ± SEM from triplicate experiments. *, P<0.05; **, P<0.01; ***, P<0.001; ns, P>0.05. GEPIA, gene expression profiling interactive analysis database; PC, pancreatic cancer; qPCR, quantitative polymerase chain reaction; OS, overall survival.