Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Mar;10(6):350. doi: 10.21037/atm-22-115

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

2022 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

PMC Copyright notice

MiR-122 antagomir combined with sevoflurane further promoted the expression of miR-122 and activated the Nrf2/HO-1 signaling pathway. (A) qRT-PCR showed the miR-122 levels in liver tissue. (B) Western blot showed the expressions of Nrf2 in the nucleus, and Nrf2 in the cytoplasm and HO-1. Quantified values were mean ± standard deviation of at least three independent experiments. ^▲, P<0.05, ^▲▲, P<0.01 vs. the IR group; ^★, P<0.05, ^★★, P<0.01 vs. the IR + miR-122 antagomir group. +, this group rats were treated with indicated agent; −, this groups did not receive this indicated treatment. IR, ischemia-reperfusion; Nrf2, nuclear factor E2-related factor 2.