Table 1. Comparison of the control, pre-sarcopenia, and sarcopenia groups.
| Factors | Control (n=48) | Pre-sarcopenia (n=29) | Sarcopenia (n=33) | P value (control vs. pre-sarcopenia) | P value (control vs. sarcopenia) | P value (pre-sarcopenia vs. sarcopenia) |
|---|---|---|---|---|---|---|
| Sex | 0.139 | 0.010** | 0.316 | |||
| Male | 35 | 16 | 14 | |||
| Female | 13 | 13 | 19 | |||
| Age (years) | 46.44±12.20 | 44.17±12.27 | 39.70±17.78 | 0.433 | 0.064 | 0.249 |
| BMI (kg/m2) | 23.56±2.17 | 21.86±3.2 | 19.11±2.73 | 0.016* | <0.001** | <0.001*** |
| Smoking history | 5 (10.42%) | 5 (17.24%) | 2 (6.06%) | 0.489 | 0.695 | 0.237 |
| Alcohol consumption history | 7 (14.58%) | 5 (17.24%) | 22 (66.67%) | 0.755 | <0.001** | <0.001*** |
| Gastrointestinal surgery history | 9 (18.75%) | 11 (37.93%) | 14 (42.42%) | 0.063 | 0.020** | 0.719 |
| Parenteral manifestations | 2 (4.17%) | 7 (24.13%) | 21 (63.64%) | 0.008* | <0.001** | 0.002*** |
| IBD-related complications | 1 (2.08%) | 2 (6.89%) | 22 (66.67%) | 0.553 | <0.001** | <0.001*** |
| Alb (g/L) | 40.02±5.15 | 39.39±4.21 | 28.64±5.67 | 0.563 | <0.001** | <0.001*** |
| CRP (mg/L) | 4.35±4.19 | 5.81±4.77 | 23.39±28.88 | 0.164 | <0.001** | 0.002*** |
| ESR (mm/60 min) | 9.82±11.32 | 11.34±7.48 | 23.51±16.82 | 0.523 | <0.001** | <0.001*** |
| Fasting blood glucose (mmol/L) | 4.78±0.79 | 4.50±0.54 | 4.80±1.22 | 0.075 | 0.953 | 0.233 |
| TC (mmol/L) | 3.92±1.33 | 3.75±1.36 | 3.91±1.41 | 0.675 | 0.989 | 0.747 |
| TG (mmol/L) | 1.00±0.30 | 1.00±0.56 | 0.92±0.35 | 0.970 | 0.468 | 0.671 |
| HDL (mmol/L) | 1.25±0.46 | 1.37±0.38 | 1.20±0.44 | 0.345 | 0.754 | 0.250 |
| LDL (mmol/L) | 2.43±0.72 | 2.33±0.68 | 2.21±0.55 | 0.634 | 0.345 | 0.586 |
| ALT (IU/L) | 25.43±54.79 | 14.14±6.17 | 13.48±10.35 | 0.104 | 0.078 | 0.811 |
| AST (IU/L) | 16.80±6.39 | 15.48±4.48 | 14.94±11.45 | 0.163 | 0.189 | 0.978 |
| ALP (IU/L) | 65.87±27.07 | 62.96±16.61 | 62.84±16.49 | 0.610 | 0.574 | 0.914 |
| TBIL (µmol/L) | 12.83±7.4 | 10.21±4.19 | 10.05±6.81 | 0.053 | 0.090 | 0.685 |
| BUN (mmol/L) | 5.04±2.29 | 4.84±1.15 | 4.60±3.01 | 0.677 | 0.465 | 0.685 |
| Cr (µmol/L) | 59.86±14.53 | 55.47±11.19 | 63.88±49.86 | 0.168 | 0.655 | 0.377 |
| Hb (g/L) | 129.67±19.05 | 120.38±26.90 | 110.72±26.0 | 0.110 | 0.001** | 0.156 |
| PLT (×109/L) | 269.85±93.51 | 292.21±106.28 | 308.48±104.12 | 0.338 | 0.092 | 0.545 |
| WBC (×109/L) | 6.52±2.04 | 7.09±2.78 | 7.95±3.78 | 0.306 | 0.054 | 0.317 |
| Follow-up | ||||||
| Improvement | 22 | 10 | 7 | 0.327 | 0.023** | 0.243 |
| Changing treatment plans | 25 | 12 | 11 | 0.362 | 0.095 | 0.513 |
| Undergoing surgery | 1 | 6 | 16 | 0.010* | <0.001** | 0.022*** |
| Re-hospitalization due to recurrence | 2 | 7 | 16 | 0.008* | <0.001** | 0.048*** |
| Death | 0 | 1 | 6 | 0.377 | 0.003** | 0.109 |
Laboratory data were collected at baseline and based on a single measurement. *, control vs. pre-sarcopenia, P<0.05 was considered statistically significant; **, control vs. sarcopenia, P<0.05 was considered statistically significant; ***, pre-sarcopenia vs. sarcopenia, P<0.05 was considered statistically significant. BMI, body mass index; IBD, inflammatory bowel disease; Alb, albumin; CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; TC, total cholesterol; TG, total triglycerides; HDL, high-density lipoprotein; LDL, low-density lipoprotein; ALT, alanine aminotransferase; AST, aspartate aminotransferase; ALP, alkaline phosphatase; TBIL, total bilirubin; BUN, urea nitrogen; Cr, creatinine; Hb, hemoglobin; PLT, platelets; WBC, white blood cells.