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. 2022 Apr 1;13:842555. doi: 10.3389/fimmu.2022.842555

Table 2.

Characteristics of patients vaccinated in Phase I and Phase II studies.

N Sex Age Primary CM N AJCC stage Clinical Study DMFS OS Treatments post DM
1 M 42 T4b N2b IIIC CASVAC 2 12 QT
2 M 52 T2a N2b IIIB CASVAC 150+ 150 0
3 F 33 T4b N0 IIC CASVAC 34 47 V
4 F 41 T3b N2b III C CASVAC 141+ 141+ 0
5 F 33 T1b N1c IIIB CASVAC 136+ 136+ V, HP, N, D/TRA
6 M 61 T0 N2b IIIC CASVAC 137+ 137+ 0
7 M 48 T4b N1a III C CASVAC 94 120 RT; N; D/Tra
8 M 50 T3a N1a III B CASVAC 130+ 130+ 0
9 F 51 T3a N1a IIIB CASVAC 25 79 V
10 F 39 T2a N2a IIIB CASVAC 12 30 V
11 M 47 T3a N1a III B CASVAC 107+ 107+ 0
12 M 46 T3B N2A IIIC CASVAC 57 89+ U
13 M 35 T3a N1a III B CASVAC 101+ 101+ 0
14 M 40 T3b N3 IIIC CASVAC 10 14 RT; V
15 F 51 T4b N1a IIIC CASVAC 97+ 97+ 0
16 M 35 T3b N1b IIIC CASVAC 7 14 0
17 F 61 T4a N0 IIB CASVAC 36 77+ U
18 F 43 T2a N2c IIIC CASVAC 91+ 91+ 0
19 M 46 T4b N0 IIC CASVAC 44 91+ N
20 F 49 T? N1 IIIA VACCIMEL 216+ 216+ 0
21 M 33 T2 N0 IIB VACCIMEL 52 90 U
22 F 45 T2a N0 IIB VACCIMEL 204+ 204+ 0
23 F 33 T0 N3b IIIC VACCIMEL 112 132 I
24 F 15 T4a N2b IIIC VACCIMEL 218+ 218+ 0
25 F 56 T0 N2b IIIC VACCIMEL 213+ 213+ 0
26 F 32 T2b N1b IIIB VACCIMEL 223+ 223+ 0
27 F 48 T0 N2b IIIC VACCIMEL 218+ 218+ 0
28 M 28 T2b N1c IIIC VACCIMEL 3 28 QT
29 M 65 T4a N1c IIIC VACCIMEL 156 156 U
30 F 65 T4a N1c IIIC VACCIMEL 10 23 QT

Clinical stages were determined according to 8th edition AJCC. DMFS, distant metastasis-free survival; OS, overall survival; DM, distant metastases; 0, no treatment; HT, hyperthermic perfusion; QT, chemotherapy; V, vemurafenib; I, ipilimumab; RT, radiotherapy; N, nivolumab; D/Tra, dabrafenib/trametinib; U, unknown.