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Effect of antituberculosis agent concentration on selection of resistant mutants. M. tuberculosis isolate TN6515 was applied to agar plates containing the indicated concentrations of isoniazid (A), rifampin (B), streptomycin (C), and ciprofloxacin (D). After incubation, the number of drug-resistant colonies was recorded and was plotted relative to the number of CFU applied to drug-free agar plates.
