TABLE 2.
Homologies of the ORFs of Tn1207.1
| ORFa | Homologous geneb | Originc | Proposed function of gene product | E value | Amino acid identity | Amino acid similarity |
|---|---|---|---|---|---|---|
| orf1 (218) | None | |||||
| orf2 (370) | ccrB (AB014438) | mec DNA (S. aureus) (13) | Site-specific recombinase | 4e-18 | 93/294 (31%) | 144/294 (48%) |
| cisA (M29040) | skin element (B. subtilis) (39) | Site-specific recombinase | 2e-14 | 79/304 (25%) | 139/304 (44%) | |
| int (AJ242593) | Bacteriophage A118 (L. monocytogenes) (16) | Integrase | 6e-12 | 59/196 (30%) | 104/196 (52%) | |
| tnpX (U15027) | Transposon Tn4451 (C. perfringens) (6) | Site-specific recombinase | 1e-11 | 78/312 (25%) | 132/312 (42%) | |
| orf3 (138) | None | |||||
| mefA (405) | mef(A) (U70055) | (S. pyogenes) (8) | Macrolide-efflux protein | 0 | 405/405 (100%) | |
| orf5 (487) | msr(SA) (AB016613) | Plasmid pEP2104 (S. aureus) (22) | Macrolide-resistance protein | 6e-91 | 180/471 (38%) | 285/471 (60%) |
| vga(A) (M90056) | Plasmid pIP524 (S. aureus) (1) | Streptogramin A-resistance protein | 2e-89 | 183/485 (37%) | 283/485 (57%) | |
| orf6 (99) | orf11 (L29324) | Conjugative transposon Tn5252 (S. pneumoniae) (23) | Unknown | 2e-22 | 45/76 (59%) | 61/76 (80%) |
| orf7 (122) | orf12 (L29324) | Conjugative transposon Tn5252 (S. pneumoniae) (23) | Unknown | 3e-06 | 30/96 (31%) | 46/96 (47%) |
| orf8 (117) | umuC (L29324) | Conjugative transposon Tn5252 (S. pneumoniae) (23) | UV resistance protein | 6e-36 | 70/116 (60%) | 89/116 (76%) |
a
The number of amino acids is shown in parentheses.
b
The accession number is shown in parentheses.
c
The number in parentheses is the reference.