Table 1.
Baseline performance at end of 20 minutes stabilization.
| WT (mean ± SD) | C3KO (mean ± SD) | p-value | |
|---|---|---|---|
| Number of animals | 12 | 12 | – |
| LVEDP (mmHg) | 9.88 ± 4.3 | 8.56 ± 2.4 | 0.358 |
| Heart rate (bpm) | 340.9 ± 42.3 | 367.1 ± 71.7 | 0.287 |
| LVdevP (mmHg) | 117.5 ± 7.8 | 119.4 ± 7.7 | 0.559 |
| RPP | 40,098 + 5845 | 43,531 + 8218 | 0.251 |
| Coronary flow (ml/minute) | 2.29 ± 0.5 | 2.05 ± 0.3 | 0.205 |
| Body weight (grams) | 25.1 ± 1.9 | 26.5 ± 2.4 | 0.073 |
| Mouse age (weeks) | 8.3 ± 1.0 | 8.2 ± 0.8 | 0.962 |
LVEDP, Left-ventricular end-diastolic pressure; bpm, beats per minute; LVdevP, Leftventricular developing pressure; RPP, rate pressure product. t-tests were used to calculate the p-values.