TABLE 4.
ROC curve analysis of NLR, LDH, ferritin, AST, ALT, and procalcitonin for severe COVID‐19
| Variables | AUC | SD | 95% CI | Cut‐off | Sensitivity (%) | Specificity (%) | p‐Value |
|---|---|---|---|---|---|---|---|
| NLR | 0.757 | 0.074 | 0.708–0.972 | 8.8 | 72.7 | 75.4 | 0.007 |
| LDH (U/L) | 0.856 | 0.050 | 0.759–0.953 | 365 | 72.7 | 90.8 | <0.001 |
| ALT (U/L) | 0.771 | 0.070 | 0.632–0.909 | 16.5 | 72.7 | 70.8 | 0.004 |
| AST (U/L) | 0.840 | 0.067 | 0.759–0.953 | 34 | 72.7 | 81.5 | <0.001 |
| Ferritin (ng/ml) | 0.821 | 0.060 | 0.704–0.938 | 41.5 | 72.7 | 78.5 | 0.001 |
| Procalcitonin (ng/L) | 0.698 | 0.078 | 0.545–0.850 | 0.07 | 63.6 | 60 | 0.038 |
Note: Significant values are in bold and italics.
Abbreviations: ALT, alanine transaminase; AST, aspartate transaminase; AUC, area under the curve; CI, confidence interval; LDH, lactate dehydrogenase; NLR, neutrophil‐to‐lymphocyte ratio.