Skip to main content
. 2022 Apr 15;22:106. doi: 10.1186/s12866-022-02515-z

Table 2.

MICs and FICIs of celastrol and tested antibiotics against S. aureus ATCC 6538

Agent MIC (μg∕mL) FIC FICI Interpretation
Alone Combination
Celastrol 1 0.25 0.25 0.31 S
Ampicillin 8 0.5 0.06
Celastrol 1 0.25 0.25 0.31 S
Cefotaxime 4 0.25 0.06
Celastrol 1 0.06 0.06 0.12 S
Azithromycin 1 0.06 0.06
Celastrol 1 0.06 0.06 0.185 S
Ciprofloxacin 2 0.25 0.125
Celastrol 1 0.06 0.06 0.12 S
Gentamycin 2 0.12 0.06

FIC Fractional inhibitory concentration, FICI Fractional inhibitory concentration index, S Synergism