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. 2022 Apr 14;22:320. doi: 10.1186/s12884-022-04491-8

Table 2.

Association of fetal chromosomal abnormalities with maternal characteristics (categorical variables)

Normal Abnormal P Crude OR (95% CI)
Folic acid supplementation
 No 13 (21.7) 19 (19.0)
 Yes 47 (78.3) 81 (81.0) 0.683 1,18 (0.53, 2.60)
 Previous miscarriages (n)
  < 1 30 (50.0) 66 (66.0)
  ≥ 1 30 (50.0) 34 (34.0) 0.046 0.52 (0.27, 0.99)*
Exposure to paint
 No 59 (98.3) 92 (92.0)
 Yes 1 (1.7) 8 (8.0) 0.184 5.13 (0.63, 42.08)
Perceived noises
 No 46 (76.7) 92 (92.0)
 Yes 14 (23.3) 8 (8.0) 0.006 0.29 (0.11, 0.73)**
Pesticide exposure
 No 53 (88.3) 91 (91.0)
 Yes 7 (11.7) 9 (9.0) 0.586 0.75 (0.26, 2.13)
Repellent exposure
 No 50 (83.3) 84 (84.0)
 Yes 10 (16.7) 16 (16.0) 0.912 0.95 (0.40, 2.26)
Passive smoking
 No 26 (43.3) 45 (45.0)
 Yes 34 (56.7) 55 (55.0) 0.837 0.94 (0.49, 1.78)
Alcohol use
 No 57 (95.0) 96 (96.0)
 Yes 3 (5.0) 4 (4.0) 1.000 0.79 (0.17, 3.67)
Exposure to PAH
 No 48 (80.0) 89 (89.0)
 Yes 12 (20.0) 11 (11.0) 0.116 0.49 (0.20, 1.20)

Bold font indicates statistical significance; the 95% CI does not include 1

Abbreviations: PAH Polycyclic aromatic hydrocarbons

*indicates P < 0.05

**indicates P < 0.01